Professor Martin Scanlon
Group Leader
Monash Institute of Pharmaceutical Sciences
Monash University
martin.scanlon@monash.edu
Contract research opportunities
I am director of the Monash Research Technology Platform for fragment-based drug design (MFP). MFP curates a high-quality fragment library that has been designed to maximise chemical space coverage and enable rapid hit optimisation. Screening cascades can be tailored for any target and undertaken …using a variety of techniques including NMR spectroscopy and
surface plasmon resonance (SPR).
Structural biology and medicinal chemistry expertise utilising our
proprietary parallel chemical evolution strategy enables the rapid elaboration of fragments
into more potent lead compounds.
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Research Activities
My laboratory is principally involved in examining the interaction of small molecules with proteins. This is done using a variety of biophysical methods, primarily NMR spectroscopy.Projects involve determining the structural basis for drug protein interactions; Screening of small molecule fragments to identify novel lead compounds; Determining protein structure and dynamics and their relationship to biological activity
Techniques/Expertise
Fragment-based drug designNMR-based screening
Isotope labelling for NMR spectroscopy
Biomolecular NMR Spectroscopy
Protein expression and purification
Other Lab Members
Dr Biswaranjan MohantyDr Hong Yang
Mr Matt Bentley
Mr Wesam Alwan
Ms Rebecca Whitehouse
Dr Olga Ilyichova
Mr Stefan Nebl
Mr Ashley Taylor
Ms Beatrice Chiew
Dr Indu Chandrashekaran
