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Prof Alex Andrianopoulos

Laboratory Head
School of BioSciences
University of Melbourne

alex.a@unimelb.edu.au

Research Activities

We are studying a number of aspect of T. marneffei biology and pathogenicity and are particularly interested in understanding the molecular mechanisms which control the dimorphic switching and asexual development (conidiation) programs. Dimorphic switching is a temperature- and host-dependent response that allows T. marneffei to switch from a non-pathogenic hyphal growth form to the pathogenic yeast form. The yeast form is specialized to survive with host innate immune cells. Asexual development is the program the produce asexual spores, the infectious particles. We are teasing up the mechanisms that control these programs and examining their effects on growth and pathogenesis in the host.

Research Keywords

Researching in the following areas: Fungal pathogens, Innate immunity, Genomics, Animal Models - Zebrafish, Animal models - Mice

Techniques/Expertise

DNA-protein interactions, genomics, transcriptomics

Disease Models

Macrophage cells, zebrafish, mice

Genetically Modified Organisms

Talaromyces marneffei (formerly Penicillium marneffei), Aspergillus fumigatus, Aspergillus nidulans

Websites

biosciences.unimelb.edu.au/research/research-clusters/genetics-genomics-and-development/

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Prof Alex Andrianopoulos

Research Activities

Research Keywords

Techniques/Expertise

Disease Models

Genetically Modified Organisms

Websites

Other members with similar research interests

Dr Keith Al-Hasani

Dr Carla Bianca Victorio

Prof Stephen Turner

Dr Boris Novakovic

Dr Tony Sadler

Miss Rachel Peiris

A/Prof Mark Chong

Prof Fabienne Mackay

A/Prof Anna Coussens

Miss Vik Ven Eng

Dr Grant Jenkin

Dr Hani Hosseini Far

Ms Antara Ghoshal

Miss Michelle Clark

A/Prof Michael Gantier

Associate Professor Michelle Tate

Dr Rhys Allan

Dr Helen Stoelting

Dr Alison West

Prof Stephen Kent

Prof Tim Stinear

Dr Alec Drew

Dr Kelly Wyres

Ms Sarah Rosli

Dr Nicole De Weerd

Dr KE TANG

Dr Kate Jeffrey

Dr Catherine Kennedy

Miss Rachel Webb

Dr Scott Mueller

Dr Sara Klose

Dr Sammy Bedoui

Dr Jim Harris

A/Prof Dena Lyras

Prof Ana Traven

Miss Kathryn Prame Kumar

Prof Bryan Williams

Dr Tom Brodnicki

Dr Matt Firth

Dr Bernadette Jones-Freeman

Ms Madeleine Wemyss

Dr Alice West

Prof Roger Nation

Dr Dieter Bulach

Miss Alessandra Gatta

Dr Louis Schofield

Mr Stuart Lee

Prof Steven Gerondakis

A/Prof Motti Gerlic

Dr Thomas Angelovich

Dr Niamh Mangan

Prof Alister Ward

Ms Caitlin Rowe

Prof Di Yu

Dr Ben Croker

Dr Le Son Tran

Prof A Richard Kitching

Dr Wenyi Li

Prof Jamie Rossjohn FAA FLSW FAHMS FMedSci

Dr Simon Royce

Dr Howard Yim

Dr Dominic De Nardo

Dr Latasha Abeynaike